Vulnamin® products can be used as an adjuvant in the wound healing process.2,3,4,5
Vulnamin® products are available in four different presentations: a spray, a powder, a gel and a cream.
Vulnamin® Spray has a preventative effect on the evolution of skin lesions and can be used to protect skin integrity.2
Vulnamin® Gel can be used to help restore the microenvironment of the wound, promoting elimination of necrotic tissues and protecting skin integrity.4
Vulnamin® Powder favours production of granulation tissue and the healing process.3
Vulnamin® Cream facilitates regeneration of tissues and maintenance of the ideal moisture conditions of the wound to promote reepithelisation of cutaneous lesions.5
Wound aetiology can be accidental, intentional, or the result of a disease process. Wounds can range in depth from a break in the epithelial integrity of the skin, or can extend into subcutaneous tissue with damage to other structures such as tendons, muscles, vessels, nerves, parenchymal organs and bone.1
Depending on the length of time in which it takes them to heal, wounds will often be classified as acute or chronic.1
Impact of chronic wounds
Chronic wounds are a significant health problem that require adequate healthcare resource allocation. Chronic wounds can result in significant functional impairment, a reduction in patient quality of life, and increased financial costs for both the patient and the healthcare system.6
Wound complications are associated with longer and more intensive treatment, extended hospital stays, readmission and specialist medical or surgical intervention.7
In addition, chronic wounds have many psychosocial consequences including stress, negative mood, pain and social isolation. Care of chronic wounds such as dressing changes can negatively impact upon a patient’s daily routine through either taking time out to attend wound management procedures or through the wound dressing impacting upon daily activities.8
Vulnamin® products are medical devices that can be used as an adjuvant in the wound healing process.2,3,4,5
Vulnamin® products are available in four presentations: a spray, a powder, a gel and a cream.2,3,4,5
Vulnamin® Spray has a preventative effect on the evolution of skin lesions and can be used to protect skin integrity. It facilitates the cleaning of the wound and formation of granulation tissue and therefore skin regeneration.
Vulnamin® Spray additionally reduces inflammatory infiltrate and stimulates fibroblast production of collagen 2
Vulnamin® Powder favours production of granulation tissue and the healing process. It assists skin and connective tissue regeneration through the production of collagen.
Vulnamin® Powder favours the elimination of necrotic tissue and protects the integrity of skin.3
Vulnamin® Gel can be used to help restore the microenvironment of the wound, promoting elimination of necrotic tissues and protecting skin integrity.
Vulnamin® Gel can be used to induce autolysis and stimulate granulation of vital underlying tissue.4
Vulnamin® cream facilitates regeneration of tissues and maintenance of the ideal moisture conditions of the wound to promote reepithelialisation of cutaneous lesions.
It promotes the reconstruction of connective tissue and therefore the regeneration of epithelial cells.5
Vulnamin® induces re-epithelialisation of the wound, which is associated with a marked reduction in inflammatory infiltrate and colonisation of the lesion by newly formed vessels.11
Vulnamin® has been shown to significantly increase the coverage of wounds by granulation tissue12, even whilst debridement is underway.13
The use of Vulnamin® has not been associated with any adverse effects, intolerances or allergies.13
Vulnamin® has been clinically shown to induce a rapid and progressive reduction in wound size, and to reduce healing time of wounds.11,12,13,14
Wound size has been shown to be significantly reduced after 2 weeks of use, with a continued significant reduction after 614 and 10 weeks of use compared to baseline.11
Vulnamin® contains sodium hyaluronate and amino acids.2,3,4,5
Sodium hyaluronate is an extracellular polysaccharide and is found in every human tissue and body fluid. It is involved in every phase of tissue repair.15 Hyaluronic acid has been shown to promote cell proliferation, differentiation and motility.16
Sufficient protein is necessary for wound healing due to increased overall protein need for tissue regeneration and repair. Increased metabolic demands are made by the inflammation and cellular activity in wound healing, which may require increased protein or amino acids, vitamins and minerals.17 Glycine, leucine, proline and lysine may be involved in favouring wound healing by collagenogenesis and extracellular matrix formation.16 It is hypothesised that the availability of amino acids may improve and accelerate wound closure
Vulnamin® mechanism of action
Following clinical investigations, the image below demonstrates a possible mechanism of action for Vulnamin®.18